ea0049ep1036 | Pituitary - Clinical | ECE2017
Vorotnikova Svetlana
, Dzeranova Larisa
, Pigarova Ekaterina
, Il'in Aleksandr
, Popova Nataliya
, Vershinina Marina
, Sukhanova Olga
, Kadrina Nataliya
, Shibina Larisa
, Dedov Ivan
Introduction: Prolactin exists in various forms including the monomeric biologically active form (23 kDa) and a higher molecular weight form, bound most commonly to IgG, known as macroprolactin (>100 kDa). Macroprolactin lacks biological activity but can interfere in standard prolactin immunoassays and is one of the causes of false-positive results. In Russian Federation the most common method for macroprolactin determination is PEG precipitation test.<p class="abstext...